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Cefotaxime-d3

MCE 國際站：Cefotaxime-d3

品牌：MedChemExpress (MCE)

貨號(hào)：HY-W654101

Synonyms：Cefotaxim-d3; HR-756-d3)

純度：98.00%

運(yùn)輸條件：美國大陸的室溫；其他地方可能有所不同。

產(chǎn)品活性：Cefotaxime-d3 是氘標(biāo)記的 Cefotaxime (HY-A0088A)。Cefotaxime 是耐 β-內(nèi)酰胺酶穩(wěn)定的頭孢菌素和第三代頭孢菌素抗生素。Cefotaxime 對(duì)多種革蘭氏陽性菌和革蘭氏陰性菌具有廣譜抗生素活性。

生物活性：頭孢噻肟-d3 是氘標(biāo)記的頭孢噻肟 (HY-A0088A)。頭孢噻肟是 β-內(nèi)酰胺酶穩(wěn)定的頭孢菌素和第三代頭孢菌素抗生素。頭孢噻肟對(duì)多種革蘭氏陽性菌和革蘭氏陰性菌具有廣譜抗生素活性[1][2][3][4][5]。

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參考文獻(xiàn)：

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Woodfield JC, et al. A comparison of the prophylactic efficacy of ceftriaxone and cefotaxime in abdominal surgery. Am J Surg. 2003 Jan;185(1):45-9.
[3]. Scholz H, et al. Prospective comparison of ceftriaxone and cefotaxime for the short-term treatment of bacterial meningitis in children. Chemotherapy. 1998 Mar-Apr;44(2):142-7.
[4]. E L Francke, et al. Use of cefotaxime, a beta-lactamase stable cephalosporin, in the therapy of serious infections, including those due to multiresistant organisms. Am J Med. 1981 Sep;71(3):435-42.
[5]. Gums JG, et al. Differences between ceftriaxone and cefotaxime: microbiological inconsistencies. Ann Pharmacother. 2008 Jan;42(1):71-9.