斯達(dá)特(Starter)，國(guó)產(chǎn)抗體專家，
產(chǎn)品別名: EpCAM Recombinant Mouse mAb (S-R464)

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein that is specifically expressed in epithelial tissues and is frequently overexpressed in various human epithelial-derived tumors. It plays a complex role in cell adhesion, cell signaling, migration, proliferation, and differentiation, as well as in metastasis and cancer stem cells. EpCAM's function can vary depending on the cellular context and microenvironment, and it has been implicated in the regulation of the Wnt/β-catenin, PI3K/AKT/mTOR, and p53 signaling pathways, which are crucial in cancer development and progression. EpCAM's expression is associated with poor prognosis in certain cancers and is considered a potential therapeutic target for cancer treatment. Its roles in cancer stemness, epithelial-mesenchymal transition (EMT), and immune modulation make it a molecule of interest in oncology research.

杭州斯達(dá)特專注于抗體研發(fā)和制造，其核心團(tuán)隊(duì)深耕抗體研發(fā)十五年，提供優(yōu)質(zhì)的抗體、蛋白、試劑盒和定制服務(wù)，包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。公司建立了多物種單B細(xì)胞抗體開發(fā)平臺(tái)（兔單抗，鼠類單抗等）、傳統(tǒng)鼠單抗、重組蛋白表達(dá)平臺(tái)及完善的抗體應(yīng)用驗(yàn)證和檢測(cè)體系（包括免疫層析，酶聯(lián)免疫，流式分析，免疫組化，免疫印跡，免疫熒光，免疫沉淀等）。已正式通過歐盟98/79/EC認(rèn)證、ISO9001認(rèn)證和ISO13485認(rèn)證。 官網(wǎng)點(diǎn)擊查詢：www.starter-bio.com