斯達特(Starter)，國產抗體專家，
產品別名: GAD65 Rabbit Polyclonal Antibody

Glutamic acid decarboxylase 65 (GAD65) is an enzyme that synthesizes the inhibitory neurotransmitter γ-aminobutyric acid (GABA) from glutamate, playing a crucial role in the central nervous system. It is one of the two isoforms of glutamic acid decarboxylase, the other being GAD67. GAD65 is particularly notable for its dynamic structure and its role as a major autoantigen in type 1 diabetes (T1D), with autoantibodies against it often present before the clinical onset of the disease. Structurally, GAD65 forms obligate functional dimers and consists of three domains: the N-terminal domain (NTD), the pyridoxal-5'-phosphate (PLP)-binding domain, and the C-terminal domain (CTD). Its catalytic loop (CL) is dynamic, which contrasts with the stable conformation of GAD67's CL.

杭州斯達特專注于抗體研發和制造，其核心團隊深耕抗體研發十五年，提供優質的抗體、蛋白、試劑盒和定制服務，包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。公司建立了多物種單B細胞抗體開發平臺（兔單抗，鼠類單抗等）、傳統鼠單抗、重組蛋白表達平臺及完善的抗體應用驗證和檢測體系（包括免疫層析，酶聯免疫，流式分析，免疫組化，免疫印跡，免疫熒光，免疫沉淀等）。已正式通過歐盟98/79/EC認證、ISO9001認證和ISO13485認證。 官網點擊查詢：www.starter-bio.com