斯達特(Starter)，國產抗體專家，
產品別名: FUS Recombinant Rabbit mAb (S-1015-21)

FUS (Fused in Sarcoma) is a multifunctional, predominantly nuclear DNA/RNA binding protein that plays a significant role in various cellular processes, including transcription, RNA splicing, and mRNA transport1. It belongs to the FET (FUS/EWS/TAF15) family of proteins and contains several functional domains that facilitate its interactions with nucleic acids, such as an RNA recognition motif (RRM) and a zinc finger domain. Mutations or abnormal expression of FUS have been implicated in several neurodegenerative diseases, most notably Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration (FTLD). In these diseases, FUS protein tends to form insoluble aggregates in neurons, which is thought to contribute to neuronal dysfunction and degeneration1. The exact mechanisms by which FUS contributes to disease pathology are still under investigation, but it is believed that the protein's role in RNA metabolism and its mislocalization to the cytoplasm may be key factors.

杭州斯達特專注于抗體研發和制造，其核心團隊深耕抗體研發十五年，提供優質的抗體、蛋白、試劑盒和定制服務，包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。公司建立了多物種單B細胞抗體開發平臺（兔單抗，鼠類單抗等）、傳統鼠單抗、重組蛋白表達平臺及完善的抗體應用驗證和檢測體系（包括免疫層析，酶聯免疫，流式分析，免疫組化，免疫印跡，免疫熒光，免疫沉淀等）。已正式通過歐盟98/79/EC認證、ISO9001認證和ISO13485認證。 官網點擊查詢：www.starter-bio.com