斯達(dá)特(Starter)，國產(chǎn)抗體專家，
產(chǎn)品別名: FcγRIIB Recombinant Rabbit mAb (S-R335)

Fc fragment of IgG receptor IIb (coded by FCGR2B gene) is a low affinity inhibitory receptor for the Fc region of immunoglobulin gamma (IgG). The receptor inhibits the functions of activating FcγRs, such as phagocytosis and pro-inflammatory cytokine release, mainly by clustering of FCGR2B with different activating FCGR receptors or with the BCR by immune complexes. FCGR2B regulates B cell activation by increasing the BCR activation threshold and suppressing B cell mediated antigen presentation to T cells through the ITIM-dependent inhibitory mechanism. FCGR2B expression on follicular dendritic cells (FDCs) is important for capturing the antigen-containing immune complexes which are essential for the germinal center response.

杭州斯達(dá)特專注于抗體研發(fā)和制造，其核心團(tuán)隊深耕抗體研發(fā)十五年，提供優(yōu)質(zhì)的抗體、蛋白、試劑盒和定制服務(wù)，包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。公司建立了多物種單B細(xì)胞抗體開發(fā)平臺（兔單抗，鼠類單抗等）、傳統(tǒng)鼠單抗、重組蛋白表達(dá)平臺及完善的抗體應(yīng)用驗證和檢測體系（包括免疫層析，酶聯(lián)免疫，流式分析，免疫組化，免疫印跡，免疫熒光，免疫沉淀等）。已正式通過歐盟98/79/EC認(rèn)證、ISO9001認(rèn)證和ISO13485認(rèn)證。 官網(wǎng)點擊查詢：www.starter-bio.com