斯達特(Starter)，國產(chǎn)抗體專家，
產(chǎn)品別名: FCER1A/FcεRIα Recombinant Rabbit mAb (S-1697-174)
FcεRIα (Fc epsilon receptor I alpha) is a type I transmembrane glycoprotein encoded by the FCER1A gene, which belongs to the immunoglobulin gene superfamily. It is a critical component of the high-affinity IgE receptor (FcεRI) complex, responsible for binding the Fc region of IgE antibodies with high affinity. This receptor complex is primarily expressed on mast cells and basophils, and to a lesser extent on some monocytes, Langerhans cells, dendritic cells, and eosinophils from allergic donors. Upon allergen binding to IgE, FcεRIα triggers cellular activation, leading to the release of mediators such as histamine and cytokines, which drive allergic responses and contribute to anti-parasite immunity.
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