斯達特(Starter)，國產抗體專家，
產品別名: EWSR1/EWS Recombinant Rat mAb (S-R201)

Ewing’s sarcoma (EWS) is a bone cancer arising predominantly in young children. EWSR1 (Ewing Sarcoma breakpoint region 1/EWS RNA binding protein 1) gene is ubiquitously expressed in most cell types, indicating it has diverse roles in various cellular processes and organ development. Recently, several studies have shown that missense mutations of EWSR1 genes are known to be associated with central nervous system disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Otherwise, EWSR1 plays epigenetic roles in gene expression, RNA processing, and cellular signal transduction. Interestingly, EWSR1 controls micro RNA (miRNA) levels via Drosha, leading to autophagy dysfunction and impaired dermal development. Ewsr1 deficiency also leads to premature senescence of blood cells and gamete cells with a high rate of apoptosis due to the abnormal meiosis [PMID: 30481590].

杭州斯達特專注于抗體研發和制造，其核心團隊深耕抗體研發十五年，提供優質的抗體、蛋白、試劑盒和定制服務，包括科研抗體、CDx和IVD抗原和抗體原料、一步法ELISA試劑盒、鼠兔通用二抗試劑盒以及其他用途的免疫試劑整體解決方案。公司建立了多物種單B細胞抗體開發平臺（兔單抗，鼠類單抗等）、傳統鼠單抗、重組蛋白表達平臺及完善的抗體應用驗證和檢測體系（包括免疫層析，酶聯免疫，流式分析，免疫組化，免疫印跡，免疫熒光，免疫沉淀等）。已正式通過歐盟98/79/EC認證、ISO9001認證和ISO13485認證。 官網點擊查詢：www.starter-bio.com