斯達特(Starter),國產抗體專家,
產品別名: EGFR Recombinant Rabbit mAb,PBS Only (SDT-R110)
The epidermal growth factor receptor (EGFR) is a growth factor receptor that induces cell differentiation and proliferation upon activation through the binding of one of its ligands. The receptor is located at the cell surface, where the binding of a ligand activates a tyrosine kinase in the intracellular region of the receptor. This tyrosine kinase phosphorylates a number of intracellular substrates that activates pathways leading to cell growth, DNA synthesis and the expression of oncogenes such fos and jun [PMID: 9496384].
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