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銷售商: 杭州斯達特生物科技有限公司 | 查看該公司所有產品 >> |
斯達特(Starter),國產抗體專家,
產品別名: DR5 Recombinant Rabbit mAb (S-649-36)
DR5 is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. Mice have a homologous gene, tnfrsf10b, that has been essential in the elucidation of the function of this gene in humans. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
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