細胞死亡的多條通路: 獲得對細胞凋亡,壞死和自噬的深刻認識和最新視角
The Many Roads to Cell Death: Gaining a Practical Understanding of Apoptosis, Necrosis, and Autophagy
本文摘自:Science Mag
細胞死亡是生命周期的一部分。在近幾年,對于細胞死亡途徑的研究已經戲劇化的轉變成對于非凋亡途徑的探索,包括壞死-凋亡和自噬,并且對凋亡通路的機制有了更深刻的認識。目前已經通過最前沿的技術進行了新的研究和發現,尤其是在細胞計數和細胞死亡特異性標志物領域。在這個網絡課堂中,演講嘉賓將和大家一起討論細胞死亡通路的最新視角,包括每個通路特征性的分子標志物和細胞的變化。在這個講座中,我們可以學到很實用的細胞計數為基礎的方法對細胞死亡通路進行詳細的分析,還可以了解如何分析數據以更好的了解腫瘤等疾病的病理學機制,并為藥物研發篩選出新的靶標。
本次講座已于2014年6月4日(周三)9:00 a.m.上線,此后您仍可以注冊觀看錄播。
在這個網絡課堂中,演講嘉賓將會介紹:
1. 不同細胞死亡途徑的最新視角;
2. 展示他們在細胞死亡機制和影響研究中的最新數據;
3. 講述研究細胞死亡通路的技術;
4. 實時回答在線問題(僅在線直播時間)。
關于演講嘉賓
John Abrams, Ph.D.
University of Texas Southwestern Medical Center
Dallas, TX
Dr. Abrams completed his Ph.D. at Stanford University in California after completing his undergraduate degree at Cornell University in Ithaca, New York. He joined the University of Texas Southwestern Medical Center in 1994 as an assistant professor in the Department of Cell Biology, becoming an associate professor in 2000 and program chair of the genetics and development graduate program in 2004. Dr. Abrams has been professor of cell biology since 2006; his research examines the in vivo molecular networks involved in cell death regulation and explores determinants of chromatin organization, using Drosophila as a model system. Dr. Abrams is an Ellison Foundation Scholar and a member on the Faculty of 1000. His publication record includes invited book chapters and many top international peer-reviewed journals; he also holds three patents.
William G. Telford, Ph.D.
National Institutes of Health
Bethesda, MD
Dr. William Telford received his Ph.D. in microbiology from Michigan State University in 1994, where his laboratory developed some of the earliest techniques for flow cytometric detection of apoptosis. He received his postdoctoral training in immunology at The University of Michigan Medical School, and was appointed assistant scientist at the Hospital for Special Surgery in New York City from 1997 to 1999. Dr. Telford became a staff scientist at the National Cancer Institute, National Institutes of Health in 1999, and is currently the director of the flow cytometry core laboratory in the NCI Experimental Transplantation and Immunology Branch. Dr. Telford’s main research interests include: instrument development, particularly in the area of novel solid state laser integration into flow cytometers; flow cytometric stem cell detection and characterization; and functional characterization of early apoptosis by flow and image cytometry.
Moderator: Tianna Hicklin, Ph.D.
Science/AAAS
Washington, DC
Dr. Hicklin studied biology at Colorado State University for her undergraduate education before earning a Ph.D. in neuroscience from the University of Colorado Anschutz Medical Campus. Prior to joining Science/AAAS, she worked as a science writer intern for the University of Colorado’s Office of Media and Public Relations in Denver, Colorado and for Brookhaven National Laboratory’s Media and Communications Office in Upton, New York. Dr. Hicklin is currently the assistant editor for the Science/AAAS Custom Publishing Office.
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